Tuesday, November 8, 2011

Photoactivatable Caged Cyclic RGD Peptide for Triggering Integrin Binding and Cell Adhesion to Surfaces

This ChemBioChem paper uses an immobilized photocaged peptide to photochemically control cell adhesion. The authors also show that the amount and location of cells could be controlled. This could be a new technology in tissue engineering or cell biology.
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1 comment:

  1. Nicole CogginsNovember 15, 2011 at 5:28 PM

    This is pretty cool. I would have liked to see more interesting shapes to really show the power of this approach. Is it possible to etch small patterns with the light source? The author said that after 90 minutes, 92% of all the peptides where decaged. Is that slow for decaging?

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