Friday, November 25, 2011

In-cell click labelling of small molecules to determine subcellular localisation


Bioconjugation and live cell imaging was a topic discussed in class. This paper introduces an example of conjugating a fluorometric dye to a NS5A inhibitor, which blocks the Hepatitis C virus (HCV) replication, and image where the HCV replication was held inside hepatoma derived cells. 

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