This paper reminded me of the lecture presented by the PLU speaker last year. They are able bind DNA to two carbon nanotubes and detect the conductivity of the DNA. With this setup they can detect whether the DNA has been methylated or not. The methylated DNA along with M. Sssl causes a conformational change that decreases the conductivity of the DNA.
I think this is really cool, and if the methyltransferase was coupled to a molecular logic gate this tool could be used in computing. Imagine a demethylase under control of a different logic gate for the same DNA-CNT structure. You could switch on and off electrical signals.
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