This blog supports the CH795 Special Topics in Chemistry courses taught by Dr. Gavin Williams and Dr. Alex Deiters at North Carolina State University. Please include an illustrative figure when you post a blog entry.
Monday, October 24, 2011
Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase
This paper analyzes with the hydrophobic in an attempt to better model it. Current modeling of the hydrophobic effect for biological application is incomplete and these researchers find it may be partially wrong. They find that the effect stretches further than just the water molecules adjacent to the hydrophobic components and also analyze the effects on the binding pocket.
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