Parts-Based Assembly of Synthetic Transmembrane Proteins in Mammalian Cells

This Synthetic Biology paper looks at membrane targeting using a "parts" approach. It was determined that the only necessary part was a transmembrane helix to target proteins to membranes. I found this article interesting because part of my proposal depended on the ability to target proteins to the outside of the cells. It will be interesting to see how these studies progress to investigate signaling and orientation of assembled parts.