Synthetic genetic circuits are of great interest in synthetic biology research. These circuits have been employed for a variety of functions from memory devices to sensing cancer cells towards their death or disablement. Using the tools of synthetic biology Bhomkar et al. were able to create a novel E. coli strain that can be used as a highly specific, simple and inexpensive chemical recording device. This device allows for the determination of when and what chemical the strain has been exposed to. Upon exposure to a signal molecule, it generates a quantifiable phenotypic response allowing for estimation of the time of the signal exposure.
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